Know Your Chems- Drug Interactions

Drug Interactions

It didn't occur to me that there were no threads on this subject until spring rolled around and I had hop on the Claritin again. But a lot of research chems and PCT products have interactions with prescription meds and OTC products (even cold/sinus medicines).

Anastrozole (Arimidex)
Tamoxifen
Tamoxifen- may speed up how quickly your liver processes Arimidex, decreasing the beneficial effects.
Learn more: http://www.webmd.com/drugs/drug-4363...G&pagenumber=9

Aromasin (Exemstane)
May have interactions with tamoxifen, estrogens (e.g., ethinyl estradiol, conjugated estrogens), rifampin, phenytoin, carbamazepine, phenobarbital, St John's wort.



Bromocriptine (Parlodel)
Combining alcohol with Parlodel can cause blurred vision, chest pain, pounding heartbeat, throbbing headache, confusion, and other problems. Do not drink alcoholic beverages while taking Parlodel.

Certain drugs used for psychotic conditions, including Thorazine and Haldol, inhibit the action of Parlodel.
Other drugs that may interact with Parlodel include:
Blood pressure-lowering drugs such as Aldomet and Catapres
Metoclopramide (Reglan)
Oral contraceptives
Other ergot derivatives such as Hydergine
Pimozide (Orap)
Products containing pseudoephedrine (may increase risk of toxic side-effects)[http://www.rxlist.com/script/main/sr...seudoephedrine for list of products containing pseudoephedrine)

Serious interactions may occur when combining bromo with: ergot alkaloids (e.g., ergonovine), "triptans" (e.g., sumatriptan, frovatriptan).

Drugs that cause drowsiness can increase the drowsiness caused by bromo:
drugs that cause drowsiness such as:
certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenytoin), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, nortriptyline, trazodone).


Cabergoline (Dostinex)
This drug should not be used with the following medications because very serious interactions may occur: certain medications for mental/mood disorders (e.g., phenothiazines such as chlorpromazine and promethazine, butyrophenones such as haloperidol, thioxanthenes such as thiothixene and chlorprothixene), metoclopramide.


Clenbuterol
The effect of Clenbuterol may be decreased and the bronchodilaing effect may even disappear during combined therapy with betaadrenergic blockers. Simultaneous administartion of Clenbuterol with cardiac glucosides provokes disturbances of the cardiac rhythm and increases their toxicity. Rhythmic disturbances are also observed after combined therapy with MAO-inhibitors and theophylline. Clenbuterol weakens the effects of insulin and sulfanylurea antidiabetic drug. Clenbuterol and sympatomimetics potentiate mutually their toxicity.

Clomiphene Citrate (Clomid)
Drug interactions with clomiphene citrate tablets USP have not been documented.

Ephedrine
While no specific interactions (positive or negative) between the herb ephedra and conventional medications have been reported in the literature, the active ingredients of ephedra, ephedrine and pseudoephedrine (available in a number of over-the-counter and prescription products for weight loss or nasal congestion), have been associated with several serious drug interactions. We may assume, for safety's sake, that those drugs that interact with ephedra's active ingredients may also interact with the herb ephedra. Medications for which there are well-documented interactions with ephedra's active ingredients include:

Amphetamine and Amphetamine derivatives (such as dextroamphetamine sometimes used for attention deficit hyperactivity disorder and narcolepsy)
Antidepressants ; namely, those in the class of tricyclics (such as clomipramine, desipramine, doxepin, imipramine, and nortriptyline) and monoamine oxidase inhibitors (MAOIs, including phenelzine and trancylcypromine)
Aspirin
Blood Pressure Medications , particularly clonidine
Caffeine and Guarana (a caffeine-containing herb)
Narcotics , such as morphine and codeine, prescribed for pain; codeine may also be prescribed for cough
Phenylpropanolamine (also known as norephedrine, found in certain supplements); formerly in many over the counter and prescription remedies for cough and cold; was removed from the market by the FDA because of risk of bleeding stroke. Norephedrine found in certain dietary supplements for weight loss can cause liver damage.
Theophylline (used for asthma)


Letrozole (Femara)
Letrozole or Femara affects hormonal levels and any drug that also affects hormonal levels can complicate the therapy.
Tamoxifen- may speed up how quickly your liver processes letro, decreasing the beneficial effects.
Learn more: http://www.webmd.com/drugs/drug-4363...G&pagenumber=9

Raloxifene (Evista)
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking raloxifene, it is especially important that your health care professional know if you are taking any of the following:

Cholestyramine (e.g., Questran)—Cholestyramine can significantly reduce the absorption of raloxifene
Estrogens, injection (e.g., Premarin) or
Estrogens, oral (e.g., Premarin, Estrace, Estratab) or
Estrogens, transdermal (e.g., Climara, Estrace, Vivelle)—Raloxifene should not be used with estrogens
Warfarin (e.g., Coumadin)—Raloxifene may decrease the effect of warfarin, and the dose of warfarin may need to be adjusted when adding or stopping raloxifene



Selegiline (Emsam)
This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur: other antidepressants (e.g., TCAs such as amitriptyline/nortriptyline, nefazodone, SSRIs such as citalopram/fluoxetine/paroxetine, duloxetine, mirtazapine, venlafaxine), appetite suppressants (e.g., diethylpropion, sibutramine), drugs for attention deficit disorder (e.g., atomoxetine, methylphenidate), certain antihistamines (e.g., azatadine), bronchodilators (e.g., albuterol, salmeterol), bupropion, buspirone, carbamazepine, oxcarbazepine, cyclobenzaprine, dextromethorphan, certain drugs for glaucoma (e.g., apraclonidine, brimonidine), certain drugs for high blood pressure (e.g., guanethidine, methyldopa), certain narcotic medications (e.g., meperidine, methadone, propoxyphene), nasal decongestants (e.g., pseudoephedrine, phenylephrine, phenylpropanolamine, ephedrine), certain drugs for Parkinson's disease (e.g., entacapone, levodopa, oral selegiline, tolcapone), St John's wort, street drugs (e.g., MDMA/"ecstasy", LSD, mescaline), stimulants (e.g., amphetamines, cocaine, dopamine, epinephrine, phenylalanine), "triptan" migraine drugs (e.g., sumatriptan, rizatriptan), tramadol, tyrosine, tryptophan.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenytoin), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine, fentanyl), psychiatric medicines (e.g., chlorpromazine, lithium, risperidone, trazodone).

Check the labels on all your medicines (e.g., allergy medications, cough-and-cold products, decongestants, diet pills) because they may contain dextromethorphan, decongestants, stimulants, or drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

It is very important that you follow special dietary restrictions in order to limit the amount of tyramine in your diet. Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas) or eating large amounts of chocolate. Caffeine can increase the side effects of this medication. Foods and beverages high in tyramine should be avoided while you are taking this medication and for at least 2 weeks after you stop using this medication.

Foods high in tyramine include: aged cheeses (cheddar, camembert, emmenthaler, brie, stilton blue, gruyere, gouda, brick, bleu, roquefort, boursault, parmesan, romano, provolone, liederdranz, colby, edam), aged/dried/fermented/salted/smoked/pickled/processed meats and fish (includes bacon, summer sausage, liverwurst, hot dogs, corned beef, pepperoni, salami, bologna, ham, mortadella, pickled or dried herring), banana peel, beef/chicken liver (stored, not fresh), bouillon cubes, commercial gravies, concentrated yeast extracts, fava beans, Italian green beans, broad beans, fermented bean curd, homemade yeast-leavened bread, kim chee (Korean fermented cabbage), orange pulp, overripe or spoiled fruits, packaged soups, red wine, sauerkraut, sherry, snow pea pods, sourdough bread, soy sauce, soybeans, soybean paste/miso, tofu, tap beer and ale, vermouth.

Moderate-to-low tyramine content foods include: alcohol-free beer, avocados, bananas, bottled beer and ale, chocolate and products made with chocolate, coffee, cola, cultured dairy products (e.g. buttermilk, yogurt, sour cream), distilled spirits, eggplant, canned figs, fish roe (caviar), green bean pods, pate, peanuts, port wine, raisins, raspberries, red plums, spinach, tomatoes, white

Tamoxifen (Nolvadex)
If Nolvadex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nolvadex with the following:

Aminoglutethimide (Cytadren)
Blood-thinning drugs such as Coumadin
Bromocriptine (Parlodel)
Cancer drugs such as Cytoxan
Letrozole (Femara)
Phenobarbital
Rifampin (Rifadin)


References:
http://www.rxlist.com
http://pdrhealth.com
http://webmd.com
http://www.umm.edu
http://bigogenicstimulants.com

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Another great post bro

Kartel

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VET at a few,VIP at couple prolly Elite somewhere else.

Integrity and loyalty are the foundation of my character.
Tired does not mean weak,injured does not mean weak,only WEAK means WEAK
-"Persaverance is not a long race,but many short ones right after another."-Walter Elliot-

this is some good info, thanks for posting this.

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Weights Wimmin Beer Metal

First time reading this, great info dude.

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"I came to realize that life lived to help others is the only one that matters and that it is my duty...This is my highest and best use as a human."
-Ben Stein

Great info; May have to hijack it over to my home board!

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VIP@MAS
SENIOR VET@HCM
VET@VIP

excellent post

hijack away... thats what its there for

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