Like anything Its a risk I have done this On grayhound But i had it in my back pack that stayed with me The whole Time. I Was Nervous the entire trip which any where on Greyhound is LONG.. But that was long ago when I was stupid now if I would have to travel i would just preload what i needed and thats it Dont even pack cotton balls ect.. buy thous supplies when you get to where ever you are going.JMO